2. NEOPLASMS (140-239)
1. Content:
This chapter contains the following broad groups:
140-195 Malignant neoplasms, stated or presumed to be primary, of specified sites, except of lymphatic and hematopoietic tissue
196-198 Malignant neoplasms, stated or presumed to be secondary, of specified sites
199 Malignant neoplasms, without specification of site
200-208 Malignant neoplasms, stated or presumed to be primary, of lymphatic and hematopoietic tissue
209 Neuroendocrine tumors
210-229 Benign neoplasms
230-234 Carcinoma in situ
235-238 Neoplasms of uncertain behavior [see Note, at beginning of section 235-238]
239 Neoplasms of unspecified nature
2. Functional activity
All neoplasms are classified in this chapter, whether or not functionally active. An additional code from Chapter 3 may be used to identify such functional activity associated with any neoplasm, e.g.:
catecholamine-producing malignant pheochromocytoma of adrenal:
code 194.0, additional code 255.6
basophil adenoma of pituitary with Cushing's syndrome:
code 227.3, additional code 255.0
3. Morphology [Histology]
For those wishing to identify the histological type of neoplasms, a comprehensive coded nomenclature, which comprises the morphology rubrics of the ICD-Oncology, is given after the E-code chapter.
4. Malignant neoplasms overlapping site boundaries
Categories 140-195 are for the classification of primary malignant neoplasms according to their point of origin. A malignant neoplasm that overlaps two or more subcategories within a three-digit rubric and whose point of origin cannot be determined should be classified to the subcategory .8 "Other." For example, "carcinoma involving tip and ventral surface of tongue" should be assigned to 141.8. On the other hand, "carcinoma of tip of tongue, extending to involve the ventral surface" should be coded to 141.2, as the point of origin, the tip, is known. Three subcategories (149.8, 159.8, 165.8) have been provided for malignant neoplasms that overlap the boundaries of three-digit rubrics within certain systems. Overlapping malignant neoplasms that cannot be classified as indicated above should be assigned to the appropriate subdivision of category 195 (Malignant neoplasm of other and ill-defined sites).
BENIGN NEOPLASMS (210-229)
Excludes:
cyst (of):
jaw (526.0-526.2, 526.89)
oral soft tissue (528.4)
radicular (522.8)
Excludes:
benign stromal tumors of digestive system (215.5)
Includes:
cartilage (articular) (joint)
periosteum
Excludes:
cartilage of:
ear (215.0)
eyelid (215.0)
larynx (212.1)
nose (212.0)
exostosis NOS (726.91)
synovia (215.0-215.9)
Includes:
angiolipoma
fibrolipoma
hibernoma
lipoma (fetal) (infiltrating) (intramuscular)
myelolipoma
myxolipoma
Includes:
blood vessel
bursa
fascia
ligament
muscle
peripheral, sympathetic, and parasympathetic nerves and ganglia
synovia
tendon (sheath)
Excludes:
cartilage:
articular (213.0-213.9)
larynx (212.1)
nose (212.0)
connective tissue of:
breast (217)
internal organ, except lipoma and hemangioma - code to benign neoplasm of the site
lipoma (214.0-214.9)
Includes:
blue nevus
dermatofibroma
hydrocystoma
pigmented nevus
syringoadenoma
syringoma
Excludes:
skin of genital organs (221.0-222.9)
Breast (male) (female)
connective tissue
glandular tissue
soft parts
Excludes:
adenofibrosis (610.2)
benign cyst of breast (610.0)
fibrocystic disease (610.1)
skin of breast (216.5)
Includes:
fibroid (bleeding) (uterine)
uterine:
fibromyoma
myoma
Use additional code to identify any functional activity (256.0-256.1)
Excludes:
cyst:
corpus albicans (620.2)
corpus luteum (620.1)
endometrial (617.1)
follicular (atretic) (620.0)
graafian follicle (620.0)
ovarian NOS (620.2)
retention (620.2)
Includes:
adenomatous polyp
benign teratoma
Excludes:
cyst:
epoophoron (752.11)
fimbrial (752.11)
Gartner's duct (752.11)
parovarian (752.11)
Excludes:
cartilage of eyelid (215.0)
eyelid (skin) (216.1)
optic nerve (225.1)
orbital bone (213.0)
Excludes:
hemangioma (228.02)
neurofibromatosis (237.70-237.79)
peripheral, sympathetic, and parasympathetic nerves and ganglia (215.0-215.9)
retrobulbar (224.1)
Use additional code to identify any functional activity
Use additional code to identify any functional activity
Excludes:
ovary (220)
pancreas (211.6)
testis (222.0)
Includes:
angioma (benign) (cavernous) (congenital) NOS
cavernous nevus
glomus tumor
hemangioma (benign) (congenital)
Excludes:
benign neoplasm of spleen, except hemangioma and lymphangioma (211.9)
glomus jugulare (227.6)
nevus:
NOS (216.0-216.9)
blue or pigmented (216.0-216.9)
vascular (757.32)

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